Leading cause of liver transplants
Hepatitis C can remain silent for 20 to 30 years, but all the while, fibrosis, or scar tissue, can be brewing that can eventually stop the liver from functioning.
“One of five people with chronic hepatitis C will get severe consequences to their health, Schreibman said. “Hepatitis C is responsible for 10,000 to 20,000 deaths annually and it’s the most common reason for liver transplantation in the U.S.”
Roughly 16,000 to 18,000 people await liver transplants every year, with only about 6,000 people receiving them, he said. Of the 25 to 30 liver transplants done at Hershey annually, most are because of hepatitis C, he said.
“People are dying while they wait,” Schreibman said. “I encourage organ donation every chance I get.”
Not everyone who is exposed to hepatitis C develops a chronic condition. About 15 to 20 percent of those infected will clear the virus on their own, but the majority will become chronic carriers who are likely to develop serious complications, Matisse said.
Testing involves a simple finger prick that can show results in 20 minutes. If positive for exposure to hepatitis C, a follow-up blood test will be needed to see whether the disease is active, she said.
“Usually people who have had risky behavior like IV drug use know they are at risk for it, but other people, like those who had a blood transfusion before 1992, may not even remember they had one,” Matisse said.
People often don’t want to admit they are at risk, so a blanket testing recommendation for a population known to be at high risk is a good idea, said Dr. John Goldman, infectious disease specialist with PinnacleHealth System in Harrisburg.
“There is a huge stigma attached to IV drug use so many people don’t want to tell their doctors about that,” he said. “Also, if someone used IV drugs 20 years ago and they never got sick, they may believe they’re not at risk. In reality, probably about 80 percent of all IV drug users eventually become infected. The problem is you don’t know you have it until your liver stops working.”
Treatment brings cure
While finding out you have hepatitis C may be unsettling, most of the time, the disease can be effectively treated with a combination of three medications given over six months to a year.
However, the existing treatments can cause some pretty nasty side effects, such as fatigue, nausea, depression and anemia. Because of the side effects, doctors said it can be challenging to get people to complete the treatment.
“Fortunately there are a whole slew of new drugs in the pipeline with fewer side effects and better cure rates,” Goldman said.
“Hepatitis C is evolving into a very treatable disorder, with cure rates of 90 to 100 percent in preliminary studies of these new drugs,” Schreibman said. “It’s a very exciting time for us.”
Matisse invited anyone interested in the next round of free testing at Jackson Siegelbaum or in more information about its Hepatitis C. Support Group, which is on hiatus due to dwindling attendance, to call the office information line at 717-525-6445.