Souad R Sennoune & Raul Martinez-Zaguilan
https://m.youtube.com/watch?v=iqaXXxp2GgE
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Leave a tributeSouad R Sennoune & Raul Martinez-Zaguilan
这几年没有联系,不曾想到他已重病缠身,怎么也无法与他那高大威武的形象联系起来。
记得那是在2002年,在谢教授的恩师--戴寅先生(国务院参事)的介绍下,我们在上海相识了。后来,他多次访问上海,我也应邀到他的实验室做访问学者。我们成为了好朋友。
谢教授不仅学识渊博、事业有成,并且非常热爱生活,他为人谦和、率直,脸上永远洋溢着阳光般灿烂的微笑,让人感觉无比温暖。
我们为失去这样一位好朋友、好师长、好教授而哭泣!
谢教授安息吧!我们永远怀念您!
戴秋萍,2020.1.27,于上海,同济大学
以后我们和子建夫妇成了邻居,朋友。我们一起玩牌,散步,踏青,赏秋,打排球,打高尔夫球,带孩子们一起到密西根湖边野营。
子建,你是我们20多年的朋友,你给我们留下许多美好的记忆,你永远活在我们心中!
谢建珍,陈晓路
We live in a small Midwest town with few residents of Asian descent. One day in 1999, we went to a new subdivision to look for a house. As we drove through the neighborhood, we saw an Asian looking man playing basketball with his young sons in their driveway. The younger son was my older son’s age, 7, 8 years old. Although we didn’t talk, the scene gave us a sense of warmth and safety. So we decided to buy a house in the neighborhood. That was the first time we saw Zijian.
Later on, Zijian and his family became our neighbors and friends. Together, we played cards, walked, hiked to enjoy the spring flowers and fall colors, played volleyball, golf, and took the kids camping on Lake Michigan…
Zijian, you have been our friend for over 20 years and have left us many beautiful memories, you will be forever in our heart!
Jianzhen Xie & Xiaolu Chen
My Best Friend Zijian
The picture of smiling Zijian brings vivid memory of his trademark, yet a deep sadness creeps in my heart and I couldn't help blaming him for presenting such a heavy topic to me, life and death, only this time Zijian isn't there to help me.
Zijian is one of my best friends, which I have much stringent criteria more than just dining, wining, partying, which are important for being friends. Zijian is really an excellent party animal, he has the ability to enjoy the finer things in life and he can bring his friends into the enjoyment as well, an quality not too many people possess.
A best friend is more, a best friend has the ability to impact your life journey, like Zijian.
Zijian was ahead of me for 2-3 years in graduate school, so when I graduated, he was already joined the ranks of junior bosses. At that time, the Chinese economy just began to take off and Zijian was quick to feel the excitement and explored the feasibility of a biotech venture in China with local business leaders. I was part of the team Zijian had assembled and had opportunity to witness his business acumen in first hand. Although the venture didn't fly for various reasons and Zijan decided to focus on his academic career instead. But this invaluable experience with Zijan planted an entrepreneur bug in my heart. I eventually started my own biotech company after I left Toledo.
That shared experience with Zijian was instrumental for my career selection and changed my life forever. Thank you, Zijian.
A best friend can help you to understand and enjoy life better, like Zijian.
Zijian is known for his bourgeois taste even in graduate school. Yet I was completely dumbfounded years later when we met again to dine in a restaurant. Zijian was already a professor then and he proudly showed off his knowledge and taste for all kinds drinks, martini for appetite, white to match with seafood, red to match with steak, the difference and beauty of whisky, rum, gin, vodka, and when to drink these. Last, but not least, dessert wine. To me, Zijian must have mastered the drinking, no wonder he became a productive professor. It also clarified my confusion i had since I started graduate school, when my advisor expressed his serious concern that no one in the lab was enjoying drinking. Now I understand, a good professor isn't measured by how many papers he has published, rather, he is judged by his appreciation of drinking culture.
Well, jokes aside, the simple fact that Zijian enjoyed and knew how to drink was the reflection of his deep appreciation of what life can provide. He treated every moment as present, just as Master Wu Gui advised in Kong Fu Panda. Even he was already ill, Zijian still organized a wonderful golf trip to North Michigan with a few friends. During the trip, he was the one to book the hotel, to show us the sites and local taste, to challenge us with golf course of various styles, to make sure every one was taken care of and happy. Best of all, to enjoy the time together. Yet he was ill and in pain the whole time.
That is Zijan I know, appreciate finer things in life and share his enjoyment with his friends.
I am greatly grateful with Zijian as our best friend. Now he moves on to somewhere else better, but we are still here to be just like him, to appreciate and to enjoy what life can and will provide.
William Lee and Hong Chang
听到您离开的消息,心中非常的难过,无法用言语表达。我们非常幸运在Marshall与您相遇,让我们永远有了一位可敬的良师益友。连日来您的音容笑貌常常浮现在我们眼前,很难控制我们的悲伤。在科学事业上您一丝不苟执著追求,生活上您风度儒雅平易近人,这些都深深影响我们并成为我们学习的榜样。
还记得在我们离开Huntington之前您在Country Club为我们送行。虽然重病在身,在我们面前您依然点着美食谈笑风生,还关心我们的生活和未来,我们牢记着您的每一句嘱咐和劝勉。您叫我们要学打Golf,我们现在已经在学习Golf了。真的不愿意接受那是我们见的最后一面。
谢教授一路走好,天堂安息。愿您的发现和研究造福人类。我们永远怀念您!
澜清,劲松
学生:朱骅,谭涛
谢宴未竟君先去
子哀尘间失俊杰
健在我辈与谁饮
兄台天堂人不缺
千年至交痛彻骨
古今佳话难再叙
金银虽多徒挂壁
润情于心泪沾襟
铭记笑颜梦颇连
拜望落日辉相映
祭酒与尔共婵娟
兄弟:金润铭
Jian was Mozart.
His mind so rare.
And G-d laid down
The wonders of the universe
At his feet.
Born to understand biology
And define love.
He stayed as long as he could –
For us.
His ideas require we incorporate
Them
Into our paradigm of understanding.
Jian took us to the edge of the known universe
And then one step beyond -
Where he wanted to be.
Science and wonder --
Shout for Joy!
He is not gone –
His love is alive in our hearts.
But the sorrow we bear -
The rain in our hearts-
Runs to the Ocean.
So deep,
The sorrow that we keep.
Be brave….darkness has its teaching.
Love never passes -
It is never gone.
It is alive in eternity.
We shall meet again, dear friend.
Composed by Mary Shapiro
It's an honor to know you and have you as our dear colleague and friend. Please accept our condolences and we will truly miss you.
Leandro Barbosa
Dear Dr. Xie,
When sending you an email, saying “Happy New Year,” your quick reply made me very happy because that indicated you were ok. Until now, I cannot believe I could not see you again. My husband and I planned to visit you during the traditional Chinese New Year. It is so sad that it could not come true.
I still remember your lecture, “No pump, no life” when I pursuit my Ph.D. degree at the University of Toledo ten years ago. That was so impressive! You are not only one of my committees, but you also are and will forever be one of my role models. I much appreciate you for recognizing me, encouraging me, and supporting me all the time. I never forget the Aha moment and the moment of truth when you came up with a fantastic idea. It is so touching that you always care about our time, our efforts, and my family that much. I have learned a lot from you, even if I missed some chance. Your enthusiasm for life and scientific research, your resilience, and your perseverance have been inspiring us. With all these incredible legacy, we will keep moving on------
The time we have is never enough.
The love we have is never-ending.
You are never forgotten, Dr. Xie.
May you rest in peace in heaven!
Dengyue and Yanling
Over the last couple of years, I also got to see him out and about on campus and in the community with his lovely wife. Dr. Xie's smile and warmth will be missed by many, including me. I am grateful that I got to learn from him. Dr. Xie's impact in this earthly world was great and will be for years to come.
My condolences to Dr. Xie's family and scientific family. - Diana Maue
Dear Zijian, You have never left in my heart. I will say a prayer. May you rest in peace and comfort. You will be sorely missed, last forever.
We just had a phone conversion with you on Dec. 28th. We scheduled to visit you in January, which now sadly became an impossible wish! You devoted your life to your loved science until the last minute. Your scientific wisdom, your never-stopping chasing truths' spirit and your full heart friendship are forever missed!
Dr. Xie, may you rest in peace.
Your friends: Maosheng Duan, Yinghong Zhang
With heartfelt sympathy.
JJ
Here from Brazil we would like to offer Yahong and his sons our deepest and most sincere condolences
Luis and Eliana
He was truly a scholar and leader at Marshall University, reorganizing MIIR and bringing together a core group of exceptional scientists to further health research. He was respected by all who came in contact with him and has left his handprint on Marshall through the many successes that he had.
Beyond the science, he was a pleasure to spend time with. He introduced me to many of the teas of China and taught me how to enjoy them. We talked about a wide range of subjects in the times I met with him, and I always learned something new each time we met. I will miss those times together.
HIs passing is a loss to all of us. Our thoughts and prayers are with his family and friends.
Good Bye Dr Xie !
Our first thoughts go to Yahong, Joe & Jeff to whom we convey our deepest condolences.
Aude & Yoann
It is so hard to believe that you are gone home, but it is easy to imagine you in heaven looking down at us with your angelic smile! Rest In Peace my dear friend ! We will miss you so dearly!
Jian: You will be forever remembered and missed by me and my wife Julie and all of your friends!
Your friend, Shaomeng Wang
哥哥:你是一个好儿子,好哥哥,好舅舅。对爸爸和姆妈,尽孝心,每次回国,都带上爸爸和姆妈,你走到哪里,就带到那里,让姆妈在一群老伙伴面前有了津津乐道的谈资。对妹妹们,总是尽最大的能力照顾。小妹妹买房子,你添砖加瓦。对外甥、外甥女,你潜心教育。李信能在很短的时间内融入高中生活,顺利考入大学,无不体现你的心血:高中时的选课,既要让李信能听懂,又要能很快掌握词汇量,你动了很多心思。当年的李信还在青春期,记得你说过,每次教育李信,都是你们俩人在喝着饮料,谈到高兴的时候讲。所以李信说舅舅就像他的父亲一样,在他成长的路上教育着、引导着,生活上关心着。
哥哥:你操心着家里的每一个人,为他们着想,唯独忘了自己。你太累了!希望你在天堂为自己活一次,想着自己就好。
妹妹:珉珉、红红
愿谢老师在天堂安息。
回忆里第一次见到您,是我去合肥新桥机场接您的那一天,我去的一路上都在纠结说英语还是说中文的问题,很紧张,但是见到您的那一刻我感觉很亲切。我带您到lab参观,中午我带着您去学校餐厅吃饭,一路上的谈话对我影响很大,您的一句话我受益终生,you must read! 我很羞愧当时的自己多么的无知,也很感谢您在我不知方向的时候指引了我。我很感谢人生中遇到你,令我的思维有了很大的转变,改变思维的意义太重大了!
实在没想到竟连再见都没有机会了,我还想再回到Huntington,去看看您,看看工作时的您,休闲时的您。没想到一别即永生,实在遗憾!
再见了,Dr. Xie!
我永远尊重您,也永远铭记您!一路走好!
Yiyao
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怀念我们的大哥哥,谢子建
今天有位朋友要去MCO就职,我就突然想起了子建大哥和亚红姐,上网去查查吧,却突然发现子建大哥过世的噩耗。心中是万般的悲伤,泪如泉涌。虽然我们认识你是在31年前,但子建大哥在我们心目当中永远是一位顶天立地的男子汉.
那是一九八九年的秋天我先生褚衍芳,被MCO录取了。只有25岁的他只身面对种种困难,要到MCO来求学。我们全家人在国内焦急地等待他的回音。他写给我的信当中详细描述了子建大哥和亚红姐去Toledo机场接他,然后带他到家里留宿。之后又帮他安排一系列的学校里注册,找公寓,直到把他安顿了下来。我们在国内都觉得非常非常的欣慰,幸运有如此的好学长。等到我来到MCO读书的时候我们都在一个系,天天可在走廊里或者是Lunch Room看到子建大哥高大的身影,和蔼可亲的笑容,听到他朗朗的笑声。记得第一次被邀请到他们家去开party,那时他们已经有两个孩子,还有房子。他们的生活就是我们这些初来乍到的学生的梦想。他们为我们做了一个非常好的榜样,让我们看到生活在这个国家也是可以非常美好的..... 很快三四年的学习就这样子结束了。毕业了我们都各奔了东西,过去的美好记忆像陈年的酒,都留在了心底,总想等时机,再回首再相聚,时间过得真是太快了,一晃都30年了,真的也没想到子建大哥就这样快地离开了我们。相聚易难,别亦难,在此真心的想告诉子建大哥,谢谢你,怀念你。
蔡路维,褚衍芳
Dear Jian,
祝贺你!!
你最崭新闪烁的生命科学理念今天 终于公布于世了。
Science Advances/Molecular Biology
Sci. Adv. 2020; 6 : eaaw5851 27 May 2020
A caveolin binding motif in Na/K-ATPase is required for stem cell differentiation and organogenesis in mammals and C. elegans
Xiaoliang Wang1*†, Liquan Cai1*, Jeffrey X. Xie2, Xiaoyu Cui1, Jue Zhang1, Jiayan Wang1,Yiliang Chen3, Isabel Larre1, Joseph I. Shapiro4, Sandrine V. Pierre1, Dianqing Wu5,Guo-Zhang Zhu1,6, Zijian Xie1
Several signaling events have been recognized as essential for regulating cell lineage specification and organogenesis in animals. We find that the gain of an amino-terminal caveolin binding motif (CBM) in the subunit of the Na/K–adenosine triphosphatase (ATPase) (NKA) is required for the early stages of organogenesis in both mice and Caenorhabditis elegans. The evolutionary gain of the CBM occurred at the same time as the acquisition of the binding sites for Na+/K+. Loss of this CBM does not affect cell lineage specification or the initiation of organogenesis, but arrests further organ development. Mechanistically, this CBM is essential for the dynamic operation of Wnt and the timely up-regulation of transcriptional factors during organogenesis. These results indicate that the NKA was evolved as a dual functional protein that works in concert with Wnt as a hitherto unrecognized common mechanism to enable stem cell differentiation and organogenesis in multicellular organisms within the animal kingdom.
Submitted 7 January 2019
Accepted 2 March 2020
Published 27 May 2020
10.1126/sciadv.aaw5851我相信,不久的将来,人们将会重新改写Na/K-ATPase对生命的意义,并应用它治疗疾病,造福于人类。
在为人类生命探讨的诗篇中,你终于可以画上一个完整的句号。
爱你,想你的Hong
Dear Jian,
Congratulations! Your newest and brightest concept of life science has finally come out.
(Sci. Adv. 2020; 6 : eaaw5851 27 May 2020)
I believe that in the near future, people will rewrite the meaning of Na/K-ATPase to life and apply it to treat diseases for the benefit of mankind. In the psalms for human life, you can finally draw a full stop.Love and miss you
Hong
首先谢谢我的公婆。是他们送给我一位,乐观,自信,宽容,有理想,有追求的儿子-谢子建。一个最美好的礼物,我亲爱的-建。
谢谢你-建,让我有幸成为你的生活伴侣。是你在所有爱慕女孩的包围之中选择了我,让我有了一个温暖,幸福的家。你对我的爱始终如一,从我们相爱后的第一次接吻到生命的最后。无论是在孩子或是朋友面前你时常会拥抱我或亲吻我,有时搞得我都不好意思。你像一个卫士一样,永远保护着我。
我们并肩走过了35年的日日夜夜,我们分享着数不尽的欢乐时光,我们有太多的共同爱好。你还是我第一个高尔夫球教练,也是最好的教练。我们共同养育了2 个儿子和2个侄儿,在你的精心培养下,他们个个聪明善良,像你一样对生活有理想,有追求。
在我们共同的道路上,无论你出现在哪里,你的周围总是有很多可亲可爱的朋友,总是冲满了温暖,欢乐。你用你的真情去爱他们,关心他们。
你是一个思维敏感聪明照人的人,你对事业的追求是哪么地热中,你从未终止过,直到最后。你告诉过我,正是因为你对科研的执着,才使你的生命支撑到今天。
你勇敢顽强地和病魔挑战争夺时间,在你生命的最后一段时间里,你无白天无黑夜地工作,想到每个为你工作的人和学生,希望为他们铺上最后的路。
你是一个意志坚强钢意过人的人。在医院那段时间,你怕止疼药影向你的思维,你总说不痛,直到最后。
你是一个永远为他人着想的人,特别是为我。当你为他人安排完毕之后,在你清醒的最后一刻,你握着我的手说:“Hong,我不能再陪伴你了。我对不起你,对不起”
昨天,当我清理我的书桌时,发现了一封不知你何时留给我的最后一封信。你写到:“ 亲爱的亚红:你是一个坚强的人。太多的爱在环绕着你;太多的心在保护着你,特别是我,特别是现在。”
亲爱的建,我知道,我们都知道,你累了,太累了,该休息了。
放心吧,我们会沿着你的路永不停步!你会永远,永远活在我,和我们的心里!
亲爱的建,你知道吗?今天有106位亲朋好友来自不同的地方用鲜花和香槟庆祝你光辉灿烂的一生。你会为自己的一生而骄傲! 我们会永远爱你!永记心中!
我真幸运能有你。谢谢你!我亲爱的-建!
你的红
02-01-2020
To my Darling-Jian
Thank you to my Dear parents-in-law, for raising a son who was confident, optimistic, warm-hearted, ambitious and aspiring. A loving gift to me, that’s you, my darling Jian.
Thank you, Jian, for having me as your wife. There were so many girls who admired you. But you chose me and gave me a happy loving home. Your love never stopped from our first kiss until the end. You kissed me all the time in front of our kids and friends even though you knew this was not customary in Chinese culture to show your love openly. You took care of me.
We walked on this earth shoulder to shoulder for 35 years, we shared many happy moments and so many hobbies together, including golf. You were my first and the best golf coach. But you did get mad when I beat you. We also raised 2 sons and 2 nephews who grew up to be kind, intelligent, and aspiring just like you.
In our time together, wherever you were, you were surrounded by many, many dearest friends. You opened your heart to them, and they filled our lives with affection and love.
You were an intelligent and aspiring scholar. You loved your work. Your passion for science was fierce and never stopped until the end. You told me, your love for science was what you could hold on to when you fought for your life.
You fought a brave battle with cancer to make the most of your time. In the last phase of your life, you worked tirelessly day and night. You cared for every student and employee who worked for you. You mentored them and helped guide their future.
You were such a tough person. When you were in the hospital, you were afraid the painkiller would have clouded your mind. So, you refused to take them until the end.
You always put others before yourself, especially me. After you made all the proper arrangements for others, you held my hands in the last moment of your life, and said: “Hong, I can’t stay with you anymore. I am sorry, I am sorry….”
Yesterday, I found a card you hid on my table. You wrote: Dear Yahong: you are a strong woman. So many loves surrounding you, So many hearts are caring for you, Especially mine, Especially now. Love, Jian
Dear Jian, I know, we all know, you were too tired. You shall rest.
Don’t worry. We will continue the path you wished. You will forever live in my heart and our hearts.
Dear Jian, today, your family and friends, either here in person or in thoughts, are here to celebrate your life and achievement. You should be proud for yourself. We all love you and will remember you forever in our hearts.
I am so lucky to have you, Thank you, my darling Jian!
Yours Hong
02-01-2020