Rev. E A Ayisi was born at Suhum on 31st August 1926 to the late Andrew Elias Ayisi and the  the late Emma Oforiwa Ayisi. He was the fifth 5th born amongst eight children. His father hailed from Aseseeso Akuapem and the mother from Adukrom Akwapem all in the Okere district of the Eastern Region of Ghana. His father was once the secretary to the Adukrom Akuapem chief.
Rev E.A. Ayisi was raised up in a Presbyterian Home (as a child) before he joined the Apostolic Church in 1948 after receiving the baptism of the Holy Spirit, an experience which profoundly affected his whole life up until he passed on to glory.
EDUCATIONAL BACKGROUND:
Rev Edward Andrew Ayisi attended the Suhum Presbyterian Elementary School from 134 to 1944 and proceeded to Accra Academy where he completed in 1949. After his Secondary Education, Rev E.A. Ayisi worked as a teacher for 4 years and had the opportunity to proceed to the School of Administration, Lego currently University of Ghana Business School to study Public Administration and continued at the University of Birmingham where he pursued a program in Government Administration.
WORKING LIFE:
After Rev Ayisi's course of study abroad, he had the opportunity to be engaged in Civil Service of Ghana and by dint of hard work and his meritorious services, rose through the Civil Service ranks to become a Principal Secretary. Rev Ayisi had apparently worked in various towns as Assistant Clerk, Swedru Urban Council from 1953 to 1956, a Clerk of Council, Awutu Local Council from1956 to 1959, a Clerk of Council.Gomoa Efutu District from 1959 to 1960, Clerk of Council in Koridua, Kumasi and Secondi/Takoradi respectively.
MARRIAGE LIFE: 
Rev. Edward Adrew Ayisi tied the knot with the late Mrs Ernestina Ayisi(nee Ernestina Debra Sapong) in 1954. She was a staunch Christian and a strong member of the Apostolic Church Ghana until she passed on to glory in 2004. He fathered 13 children,34 grandchildren and  24 great grandchildren. 
POLITICIAN
 He also became the District Chief Executive for Kwahu and Akim Oda District Councils. Having taught in the Nkumah Ideological Institute from 1965 to 1966, Rev Ayisi passion for politics emerged. After 26 years of meritorious service, Rev Ayisi voluntarily retired. He contested the Suhum Constituency as a parliamentary candidate and won. Rev Ayisi subsequently became a Member of Parliament.
In Parliament, he was appointed the Government Chief Whip during President Hilla Liman's Administration. When President Hilla Liman's government was over thrown, Reve Edward Ayisi was put in detention for a whole year, 1982 to 1983. In detention, the Lord spoke with him to prepare himself for an assignment He was soon to engage him with.
CLERGYMAN:
After his release from detention. Rev. Edward Adrew Ayisi was engaged as an Administrative Manager of The Apostolic Church- Ghana in 1986
In 1992, Rev. Ayisi was called into the ministry of The Apostolic Church- Ghana and subsequently ordained a full-time Minister. He served as district pastor of Dansoman from 1992 to 1995. Later it became necessary for the Ghana Pentecostal Council to engage a fulltime Genera Secretary to run the affairs of the council, the spot light fell on Rev. Edward Andrew Ayisi.
MUSICAL EXPLOITS:
Rev. Ayisi loved music and liked playing the piano. He composed severa charismatic songs, the popular one being "nie yehowa ahyira no , ahyira no"
AUTHOR:
He authored three books: The Five Kinds of Human Beings, Honey Moon, A Legacy of Advice to the youth which he typed on his Laptop by himself at age 94 and one Pre marital manual
"You and Your Wife"